Werdum (14-5-1 MMA, 2-2 UFC) will face Roy Nelson (16-6 MMA, 3-2 UFC) in his first Octagon appearance since leaving the Octagon in 2008. The Brazilian is best known for his 2010 armbar submission of Fedor Emelianenko which ended the champ's 27-fight winning streak.
Nelson is coming off a third-round TKO of Mirko "Cro Cop" Filipovic at UFC 137 in October. "The Ultimate Fighter 10" season winner lost his two previous bouts to Junior dos Santos and Frank Mir.
UFC 143 takes place on the eve of the Super Bowl, Feb. 4, at Mandalay Bay Events Center in Las Vegas. The fight will be available on pay-per-view.
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